Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355326710> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2355326710 abstract "Objecive: To observe the expression of mGluR5 and the dynamic regulation in the cortex of rats with focal cerebral ischemia in different phases and to investigate its significance in acute ischemia.Methods:Thirty-five male Wistar rats were raodomly divided into 11 groups: The normal contral,sham operation and ischemic operation(subdivided into 1,3,6,12 and 24-hour) by middle cerebral artery occlusion model.Brain specimens of the rats from each group were obtained for HE staining and immunohistochemistry staining.To observe the damage of neurons with light microscope and to judge the positive expression of neurons,and then to detect the changes of gray scale value in each group.Results:Compared with the normal and each sham control group,the expression of mGluR5 in each ischemia operation group was elevated 1h after ischemia and reached the peak within 12 hours after ischemia.However,there was was no significant difference between normal and sham control groups.Conclusion:Acute cerebral ischemia can cause up-regulated expression of mGluRs,suggesting that up-regulated expression of mGluR5 might be related with focal cerebral ischemia and it contributed to the development of cerebrovascular disease.According to the results of previous study,however,we presume the up-regulated expression might be the responsive increase in order to remove glutamate,which is a protect mechanism for maintain balance of organism." @default.
- W2355326710 created "2016-06-24" @default.
- W2355326710 creator A5052463631 @default.
- W2355326710 date "2007-01-01" @default.
- W2355326710 modified "2023-09-27" @default.
- W2355326710 title "The Changes of Expression of mGluR5 Induced by Acute Cerebral Ischemia in Rats" @default.
- W2355326710 hasPublicationYear "2007" @default.
- W2355326710 type Work @default.
- W2355326710 sameAs 2355326710 @default.
- W2355326710 citedByCount "0" @default.
- W2355326710 crossrefType "journal-article" @default.
- W2355326710 hasAuthorship W2355326710A5052463631 @default.
- W2355326710 hasConcept C125473707 @default.
- W2355326710 hasConcept C126322002 @default.
- W2355326710 hasConcept C142724271 @default.
- W2355326710 hasConcept C169760540 @default.
- W2355326710 hasConcept C170493617 @default.
- W2355326710 hasConcept C204232928 @default.
- W2355326710 hasConcept C2776268601 @default.
- W2355326710 hasConcept C42219234 @default.
- W2355326710 hasConcept C541997718 @default.
- W2355326710 hasConcept C61174792 @default.
- W2355326710 hasConcept C71924100 @default.
- W2355326710 hasConcept C86803240 @default.
- W2355326710 hasConceptScore W2355326710C125473707 @default.
- W2355326710 hasConceptScore W2355326710C126322002 @default.
- W2355326710 hasConceptScore W2355326710C142724271 @default.
- W2355326710 hasConceptScore W2355326710C169760540 @default.
- W2355326710 hasConceptScore W2355326710C170493617 @default.
- W2355326710 hasConceptScore W2355326710C204232928 @default.
- W2355326710 hasConceptScore W2355326710C2776268601 @default.
- W2355326710 hasConceptScore W2355326710C42219234 @default.
- W2355326710 hasConceptScore W2355326710C541997718 @default.
- W2355326710 hasConceptScore W2355326710C61174792 @default.
- W2355326710 hasConceptScore W2355326710C71924100 @default.
- W2355326710 hasConceptScore W2355326710C86803240 @default.
- W2355326710 hasLocation W23553267101 @default.
- W2355326710 hasOpenAccess W2355326710 @default.
- W2355326710 hasPrimaryLocation W23553267101 @default.
- W2355326710 hasRelatedWork W1425289167 @default.
- W2355326710 hasRelatedWork W1989877869 @default.
- W2355326710 hasRelatedWork W1992972 @default.
- W2355326710 hasRelatedWork W2370085428 @default.
- W2355326710 hasRelatedWork W2374789838 @default.
- W2355326710 hasRelatedWork W2384314554 @default.
- W2355326710 hasRelatedWork W2384926573 @default.
- W2355326710 hasRelatedWork W2395610460 @default.
- W2355326710 hasRelatedWork W2409361708 @default.
- W2355326710 hasRelatedWork W2409752272 @default.
- W2355326710 hasRelatedWork W2411844300 @default.
- W2355326710 hasRelatedWork W2589091262 @default.
- W2355326710 hasRelatedWork W3028938623 @default.
- W2355326710 hasRelatedWork W3030386459 @default.
- W2355326710 hasRelatedWork W3030779649 @default.
- W2355326710 hasRelatedWork W3030889554 @default.
- W2355326710 hasRelatedWork W3031918435 @default.
- W2355326710 hasRelatedWork W3114210849 @default.
- W2355326710 hasRelatedWork W3142463209 @default.
- W2355326710 hasRelatedWork W3145536082 @default.
- W2355326710 isParatext "false" @default.
- W2355326710 isRetracted "false" @default.
- W2355326710 magId "2355326710" @default.
- W2355326710 workType "article" @default.