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- W2355362536 abstract "Objective To investigate the relationsh ip between the changes of immunization and tissue degradation of acellular xenogen ic/allogenic dermal matrix (allo-/xeno-ADM).Methods The split thickness skin of pigs and rabbits were treated with trypsin and the xeno /allo-ADM were prepared by different methods.Based on the different pretreatme nts,following groups were designated:conjugated xeno-ADM with glutaraldahyde (group A);conjugated xeno-ADM with glutaraldahyde and punched net (group B);n o conjugated xeno-ADM (group C) and allo-ADM (group D).All samples were impla nted into dermal of different rabbits.Gross observation and histopathological e xamination were performed 4 to 32 weeks after operation.Results WT5 BZ At 4th to 12th week after implantation,foreign body giant cells existed densely in group A and group B.The degradation/assimilation level and inflamma tory reaction of ADM groups was CBAD.Linear correlation analysis revealed th at there was an apparent positive correlation (n=84,r=0.185,P0.01 ) between the densities of inflammative-immunologic cells and the degradation level of ADM.Conclusion The immunogenicity of xeno-ADM w as stronger than allo-ADM.Immunization might play an important role in the pro cess of tissue degradation.The biocompatibility of xeno-ADM was apparently not as good as of allo-ADM." @default.
- W2355362536 created "2016-06-24" @default.
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- W2355362536 date "2003-01-01" @default.
- W2355362536 modified "2023-09-27" @default.
- W2355362536 title "Study of acellular xenogenic dermal matrix degradation factor" @default.
- W2355362536 hasPublicationYear "2003" @default.
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