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- W2355372124 abstract "[Objective] To investigate the effects of acute hypervolemic hemodilution(AHH)combined with control of hypotension(CH)with nicardipine on hemodynamics in middle-aged patients and eldly patients,and evaluate its feasibility in clinical use.[Methods] Thirty ASA II patients(17 male,13 female)were enrolled in this study,15 middle-aged patients aged 40～59 years,15 eldly patients aged 65～79 years,In both groups,compound sodium aceteta injection 10 ml/kg was infused after enterring operation room.6% HES(200/0.5)15ml/kg,at rate of 30 ml/min was infused before skin incision.Nicardipine was infused at a rate of 1～4μg·(kg·min)-1 as soon as AHH began,and maintained MAP at 70% of the preoperative leavel.Hb,Hct,CO,CI,SVR,CVP,MAP,HR and blood gases were monitored and recorded before AHH(T0),AHH end(T1),AHH end 30 min(T2),AHH end 60 min(T3).CO,CI,SVR,CVP,MAP,HR were monitered at T2,T3.[Results](1)Two groups were no statistical significance regard to and the values at T0.(2)Hb、Hct:Compared with the value at T0,Hb、Hct were decreased in both groups(P0.05),Hb、Hct were no statistical significance between both groups(P0.05),(3)Hemodynamics index:Compared with the value at T0,HR、CI、CO、CVP were increased(P0.05),MAP 、SVR were decreased(P0.05 in both groups,Compared with middle-aged group,CI、CO were decreased(P0.05),CVP was increased(P0.05)at T12 、T3,MAP 、HR、SVR were no statistical significance(P0.05)in elderly patient group.[Conclusion] Hemodynamics can be maintain relatively stable in AHH combined with CH induced by nicardipine,it can be used as a way of blood conservation in elderly patients." @default.
- W2355372124 created "2016-06-24" @default.
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- W2355372124 date "2010-01-01" @default.
- W2355372124 modified "2023-09-23" @default.
- W2355372124 title "Study on the feasibility of acute hypervolemic hemodilution combined with control of hypotension with nicardipine on hemodynamics in elderly patients" @default.
- W2355372124 hasPublicationYear "2010" @default.
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