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- W2355372508 abstract "Objective To study the relationship between the expression of proliferating cell nuclear antigen (PCNA) and the development of squamous cell carcinoma of the middle ear. Methods The percentages of PCNA-positive (PCNA index) were evaluated by immunohistochemical staining. Results ①The PCNA index was significantly higher in squamous cell carcinoma than that in dysplasia mucosa of the middle ear (P 0.01 ); ②The expression of PCNA was negative in all the cases of simple hyperplasia and normal tympanic membrane; ③There was a negative correlation between PCNA indices and the histological differentiation of carcionma. The higher the PCNA indices, the poorer the differentiation of carcinoma; ④No relationship was found between PCNA indices and clinical stages. Conclusion PCNA expression may be implicated in the development and biological hehavior of the tumor." @default.
- W2355372508 created "2016-06-24" @default.
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- W2355372508 date "2000-01-01" @default.
- W2355372508 modified "2023-09-25" @default.
- W2355372508 title "Expression of proliferating cell unclear antigen in squamous cell carcinoma of the middle ear" @default.
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