Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355377669> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2355377669 abstract "Objectives:To explore the antiepileptic cellular mechanism of chronic vagus nerve stimulation (VNS). Methods: The rats were kindled by intraperitoneal injection of pentylenetetrazol (PTZ) (45mg/kg weight), and chronic VNS was applied to the kindled rats. The effects of glutamate (Glu) on the intracellular free calcium ([Ca 2+ ]i) of cortical and hippocampal neurons of normal, PTZ kindled and VNS treated rats were examined with fluorescence spectrophotometry respectively. The behavioral changes of all rats were observed. Results: The neuronal [Ca 2+ ]i of the VNS treated rats were significantly lower than that of the PTZ kindled rats. VNS could significantly inhibit the augmentation of neuronal [Ca 2+ ]i induced by Glu. Behavioral changes demonstrated that VNS could significantly reduce the severity and prolong the latency of seizures of PTZ kindled rats. Conclusions: VNS could significantly inhibit the kindling effect of PTZ and reduce the excitability of neurons induced by Glu. VNS might exerted the antiepileptic effects by influencing the activation of neural receptors." @default.
- W2355377669 created "2016-06-24" @default.
- W2355377669 creator A5075439911 @default.
- W2355377669 date "2001-01-01" @default.
- W2355377669 modified "2023-09-23" @default.
- W2355377669 title "The effect of VNS on the L-glutamate-induced augmentation of intracellular free calcium of cortical and hippocampal neurons of PTZ-kindled rats" @default.
- W2355377669 hasPublicationYear "2001" @default.
- W2355377669 type Work @default.
- W2355377669 sameAs 2355377669 @default.
- W2355377669 citedByCount "0" @default.
- W2355377669 crossrefType "journal-article" @default.
- W2355377669 hasAuthorship W2355377669A5075439911 @default.
- W2355377669 hasConcept C100691959 @default.
- W2355377669 hasConcept C126322002 @default.
- W2355377669 hasConcept C148762608 @default.
- W2355377669 hasConcept C15744967 @default.
- W2355377669 hasConcept C169760540 @default.
- W2355377669 hasConcept C170493617 @default.
- W2355377669 hasConcept C181080969 @default.
- W2355377669 hasConcept C185592680 @default.
- W2355377669 hasConcept C24998067 @default.
- W2355377669 hasConcept C2775858608 @default.
- W2355377669 hasConcept C2776819090 @default.
- W2355377669 hasConcept C2778186239 @default.
- W2355377669 hasConcept C2778302826 @default.
- W2355377669 hasConcept C2780087125 @default.
- W2355377669 hasConcept C2780159080 @default.
- W2355377669 hasConcept C2781404750 @default.
- W2355377669 hasConcept C42219234 @default.
- W2355377669 hasConcept C519063684 @default.
- W2355377669 hasConcept C55493867 @default.
- W2355377669 hasConcept C57236427 @default.
- W2355377669 hasConcept C61174792 @default.
- W2355377669 hasConcept C71924100 @default.
- W2355377669 hasConcept C98274493 @default.
- W2355377669 hasConceptScore W2355377669C100691959 @default.
- W2355377669 hasConceptScore W2355377669C126322002 @default.
- W2355377669 hasConceptScore W2355377669C148762608 @default.
- W2355377669 hasConceptScore W2355377669C15744967 @default.
- W2355377669 hasConceptScore W2355377669C169760540 @default.
- W2355377669 hasConceptScore W2355377669C170493617 @default.
- W2355377669 hasConceptScore W2355377669C181080969 @default.
- W2355377669 hasConceptScore W2355377669C185592680 @default.
- W2355377669 hasConceptScore W2355377669C24998067 @default.
- W2355377669 hasConceptScore W2355377669C2775858608 @default.
- W2355377669 hasConceptScore W2355377669C2776819090 @default.
- W2355377669 hasConceptScore W2355377669C2778186239 @default.
- W2355377669 hasConceptScore W2355377669C2778302826 @default.
- W2355377669 hasConceptScore W2355377669C2780087125 @default.
- W2355377669 hasConceptScore W2355377669C2780159080 @default.
- W2355377669 hasConceptScore W2355377669C2781404750 @default.
- W2355377669 hasConceptScore W2355377669C42219234 @default.
- W2355377669 hasConceptScore W2355377669C519063684 @default.
- W2355377669 hasConceptScore W2355377669C55493867 @default.
- W2355377669 hasConceptScore W2355377669C57236427 @default.
- W2355377669 hasConceptScore W2355377669C61174792 @default.
- W2355377669 hasConceptScore W2355377669C71924100 @default.
- W2355377669 hasConceptScore W2355377669C98274493 @default.
- W2355377669 hasOpenAccess W2355377669 @default.
- W2355377669 hasRelatedWork W1967718449 @default.
- W2355377669 hasRelatedWork W1974676021 @default.
- W2355377669 hasRelatedWork W1974995142 @default.
- W2355377669 hasRelatedWork W1977736701 @default.
- W2355377669 hasRelatedWork W1978532347 @default.
- W2355377669 hasRelatedWork W2002609171 @default.
- W2355377669 hasRelatedWork W2006262843 @default.
- W2355377669 hasRelatedWork W2018774934 @default.
- W2355377669 hasRelatedWork W2062640288 @default.
- W2355377669 hasRelatedWork W2071660528 @default.
- W2355377669 hasRelatedWork W2076710266 @default.
- W2355377669 hasRelatedWork W2289618386 @default.
- W2355377669 hasRelatedWork W2370395315 @default.
- W2355377669 hasRelatedWork W2395210942 @default.
- W2355377669 hasRelatedWork W2413246188 @default.
- W2355377669 hasRelatedWork W2550413675 @default.
- W2355377669 hasRelatedWork W3099087429 @default.
- W2355377669 hasRelatedWork W3100933055 @default.
- W2355377669 hasRelatedWork W3135390168 @default.
- W2355377669 hasRelatedWork W2166213834 @default.
- W2355377669 isParatext "false" @default.
- W2355377669 isRetracted "false" @default.
- W2355377669 magId "2355377669" @default.
- W2355377669 workType "article" @default.