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- W2355394821 abstract "Objective Using anterior segment optical coherence tomography(AS-OCT),we evaluated the effect of topical amniotic homogenate(AM) on outcomes of trabeculectomy in rabbit eyes.Methods Twenty New Zealand albino rabbits were involved in the study.The same surgeon performed bilateral standard trabeculectomy on all animals.The animals were then randomly assigned to receive topical AM or PBS(4 times a day).The filtering blebs were observed with AS-OCT and the changes of intraocular pressure were recorded.Results In animals received topical AM,the intraocular pressure decreased significantly on postoperative day 7,14 and 28,and rate of functional blebs formation was significantly higher at postoperative day 14 and 28.Conclusion Topical application of amniotic homogenate following trabeculectomy is an effective treatment to prevent conjunctival scaring,to facilitate blebs formation,and therefore to maintain a normal intraocular pressure in glaucomatous eyes.Detailed live images of the blebs can be obtained through AS-OCT." @default.
- W2355394821 created "2016-06-24" @default.
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- W2355394821 date "2013-01-01" @default.
- W2355394821 modified "2023-09-23" @default.
- W2355394821 title "Anterior segment optical coherence tomography to evaluate the effect of topical amniotic homogenate on rabbit eye following trabeculectomy" @default.
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