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- W2355413210 abstract "Objective: To investigate the effects of metoprol and fentanyl on circulatory response to tracheal intubation in hypertensive patients. Methods: 40 hypertensive patients to receive tracheal intubation anesthesia were randomly divided into four groups of 10 cases each.Before inducing anesthesia, the patients received normal saline (NS,10 mL, iv) in group A, 40 μg/kg metoprolol+NS(10 mL, iv) in group B, 2 μg/kg fentanyl+NS(10 mL, iv) in group C and 4 μg/kg metoprol + 2 μg/kg fentanyl+NS (10 mL, iv) in group D. Systolic arterial pressure(SAP), diastolic carteria pressure(DAP), heart rate (HR), rate-pressure product(RPP) and noradrenaline(NA) and adrenaline(Ad)concentrations in plasma were measured before and after intubation. Results: SAP, DAP, HR, RPP, NA and Ad levels in group A at 1 minute and 3 minutes after intubation were significantly higher than the baseline values(P0.05), NA levels in group B after intubation were significantly higher than those in group C and D (P0.05) and the hemodynamics and catecholamine levels in group D after intubation were not singnificantly different from the baselines(P0.05). Conclusion: There are markedly hemodynamic and plasma catecholamine responses to trachea intubation in hypertensive patients. 40 μg/kg metoprol or 2 μg/kg fentanyl can only partly blunt these responses, but their combination can better attenuate these responses." @default.
- W2355413210 created "2016-06-24" @default.
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- W2355413210 date "2005-01-01" @default.
- W2355413210 modified "2023-09-23" @default.
- W2355413210 title "Effects of Metoprolol and Fentanyl on Circulatory Response to Tracheal Intubation in Hypertensive Patients" @default.
- W2355413210 hasPublicationYear "2005" @default.
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