Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355452006> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2355452006 abstract "Tu-Jin-Pi, the bark of Pseudolarix kaempferi, Gord.(Pinaceae) has been used in our country for the treatment of skin diseases caused by fungi. Three novel diterpenic acids, pseudolaric acids A, B, and C were isolated from the bark. The structures of pseudolaric acid A and B were established as 1 and 2 respectively by chemical, spectral and X-ray diffraction methods.Pseudolaric acid A, C_(22)H_(28)O_6, m. p. 218～219℃ and B, C_(23)H_(28)O_8, m. p. 145～146℃. Both acids possess a methyl group attached to a tertiary carbon and a side chain with α β,γ δ-dienoic acid structure which was elucidated by ~1H NMR spectrum. Both acids possess an acetoxy functional group which may be hydrolyzed by aqueous KOH and the free alcohol reacetylated by Ac_2O-pyridine. Both acids possess a lactone ring that is resistant to hydrolysis and it was identified through IR and ~(13)C NMR spectra. The only structural difference between the two acids are located on the following parts: pseudolaric acid A(CH=CCH_3) and B(CH=CCO_2CH_3). By methylation with diazomethane, pseudolaric A forms a methyl ester, while B forms a methyl ester with the addition of another mole of CH_2N_2. The latter was shown to possess the following partial structure:The carbon skeleton was established by X-ray diffraction analysis of pseudolaric acid A. The methyl esters of deacetyl pseudolaric acid A and B were dehydrated readily with thionyl chloride-pyridine. ~1H NMR examinations on these dehydration products with INDOR technique showed that they possess the following partial structure respectively:These results further support the assignment of the structures 1 and 2 for pseudolaric acid A and B." @default.
- W2355452006 created "2016-06-24" @default.
- W2355452006 creator A5048366082 @default.
- W2355452006 creator A5060449251 @default.
- W2355452006 date "1982-01-01" @default.
- W2355452006 modified "2023-09-23" @default.
- W2355452006 title "STUDIES ON THE NOVEL DITERPENIC CONSTITUENTS OF TU-JIN-PI I. STRUCTURE OF PSEUDOLARIC ACID A AND PSEUDOLARIC ACID B" @default.
- W2355452006 hasPublicationYear "1982" @default.
- W2355452006 type Work @default.
- W2355452006 sameAs 2355452006 @default.
- W2355452006 citedByCount "0" @default.
- W2355452006 crossrefType "journal-article" @default.
- W2355452006 hasAuthorship W2355452006A5048366082 @default.
- W2355452006 hasAuthorship W2355452006A5060449251 @default.
- W2355452006 hasConcept C103319777 @default.
- W2355452006 hasConcept C111429119 @default.
- W2355452006 hasConcept C121332964 @default.
- W2355452006 hasConcept C133446333 @default.
- W2355452006 hasConcept C147789679 @default.
- W2355452006 hasConcept C163111631 @default.
- W2355452006 hasConcept C16993767 @default.
- W2355452006 hasConcept C178790620 @default.
- W2355452006 hasConcept C185592680 @default.
- W2355452006 hasConcept C24890656 @default.
- W2355452006 hasConcept C2776710815 @default.
- W2355452006 hasConcept C2776942435 @default.
- W2355452006 hasConcept C2778695967 @default.
- W2355452006 hasConcept C2779143577 @default.
- W2355452006 hasConcept C2779485729 @default.
- W2355452006 hasConcept C2780374730 @default.
- W2355452006 hasConcept C2994471683 @default.
- W2355452006 hasConcept C59822182 @default.
- W2355452006 hasConcept C71240020 @default.
- W2355452006 hasConcept C86803240 @default.
- W2355452006 hasConcept C94412978 @default.
- W2355452006 hasConceptScore W2355452006C103319777 @default.
- W2355452006 hasConceptScore W2355452006C111429119 @default.
- W2355452006 hasConceptScore W2355452006C121332964 @default.
- W2355452006 hasConceptScore W2355452006C133446333 @default.
- W2355452006 hasConceptScore W2355452006C147789679 @default.
- W2355452006 hasConceptScore W2355452006C163111631 @default.
- W2355452006 hasConceptScore W2355452006C16993767 @default.
- W2355452006 hasConceptScore W2355452006C178790620 @default.
- W2355452006 hasConceptScore W2355452006C185592680 @default.
- W2355452006 hasConceptScore W2355452006C24890656 @default.
- W2355452006 hasConceptScore W2355452006C2776710815 @default.
- W2355452006 hasConceptScore W2355452006C2776942435 @default.
- W2355452006 hasConceptScore W2355452006C2778695967 @default.
- W2355452006 hasConceptScore W2355452006C2779143577 @default.
- W2355452006 hasConceptScore W2355452006C2779485729 @default.
- W2355452006 hasConceptScore W2355452006C2780374730 @default.
- W2355452006 hasConceptScore W2355452006C2994471683 @default.
- W2355452006 hasConceptScore W2355452006C59822182 @default.
- W2355452006 hasConceptScore W2355452006C71240020 @default.
- W2355452006 hasConceptScore W2355452006C86803240 @default.
- W2355452006 hasConceptScore W2355452006C94412978 @default.
- W2355452006 hasOpenAccess W2355452006 @default.
- W2355452006 hasRelatedWork W105283946 @default.
- W2355452006 hasRelatedWork W1521716174 @default.
- W2355452006 hasRelatedWork W1930937547 @default.
- W2355452006 hasRelatedWork W1984501245 @default.
- W2355452006 hasRelatedWork W1991528319 @default.
- W2355452006 hasRelatedWork W2011937101 @default.
- W2355452006 hasRelatedWork W2013178193 @default.
- W2355452006 hasRelatedWork W2023856380 @default.
- W2355452006 hasRelatedWork W2052515448 @default.
- W2355452006 hasRelatedWork W2068405074 @default.
- W2355452006 hasRelatedWork W2079690816 @default.
- W2355452006 hasRelatedWork W2312775848 @default.
- W2355452006 hasRelatedWork W2351545649 @default.
- W2355452006 hasRelatedWork W2359035910 @default.
- W2355452006 hasRelatedWork W2363496565 @default.
- W2355452006 hasRelatedWork W2800357492 @default.
- W2355452006 hasRelatedWork W2951452222 @default.
- W2355452006 hasRelatedWork W2951532791 @default.
- W2355452006 hasRelatedWork W2953178142 @default.
- W2355452006 hasRelatedWork W3024319103 @default.
- W2355452006 isParatext "false" @default.
- W2355452006 isRetracted "false" @default.
- W2355452006 magId "2355452006" @default.
- W2355452006 workType "article" @default.