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- W2355452013 abstract "TLRs belong to the family of ancient pattern recognition proteins.Eleven TLRs have been found in mammals to date.Recognition of a wide range of viruses by TLRs can lead to the production of proinflammatory cytokines,activation of antigen presenting cells and activation of the innate and adaptive immune response.So they are recognized as the bridge between innate and adaptive immune response.TLRs can not only promote protective anti-viral immunity,but also exacerbate virus-induced diseases.In this paper,a review on the interaction between viruses and TLRs and the induced positive and negative feedback regulations is provided.This should improve our understanding of viral pathogenesis and is of significance for the development of new anti-viral therapies." @default.
- W2355452013 created "2016-06-24" @default.
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- W2355452013 date "2009-01-01" @default.
- W2355452013 modified "2023-09-25" @default.
- W2355452013 title "Progress of research on Toll like receptors and viral infection" @default.
- W2355452013 hasPublicationYear "2009" @default.
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