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- W2355455430 abstract "Objective:To observe the effect of Jiannao Mixture(JNM)in protecting mice from acute cerebral ischemia and improving learning and memory deficits.Methods:Acute cerebral ischemia in mice was induced by anoxia under ordinary pressure,sodium nitrite anoxia or decollation anoxia to observe the protective effect of JNM.Step down test and step through test were used to test the effect of JNM in improving learning and memory in mice with memory deficit induced by scopolamine,sodium nitrite or alcohol.Results:JNM(14 g/kg or 28 g/kg)could evidently prolong the survival time of acute cerebral ischemia mice,enhance the passive learning capacity,improve the impaired memory acquisition,consolidation and reviewal in mice induced by scopolamine,sodium nitrite or alcohol.Conclusion:JNM dis- plays good protection on acute cerebral ischemia mice,and could improve the learning and memory capacity in memory impaired model mice,the mechanism may be related with its effects in elevating blood oxygen level in brain and influencing central M-cholinergic sys- tem." @default.
- W2355455430 created "2016-06-24" @default.
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- W2355455430 date "2002-01-01" @default.
- W2355455430 modified "2023-09-23" @default.
- W2355455430 title "Effect of Jiannao Mixture on Protecting Mice from Acute Cerebral Ischemia and Improving Learning and Memory Deficits" @default.
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