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- W2355503883 abstract "[Objective] To discuss the effect of intestine-dredging and Qi-benefiting method and its corresponding prescription in managing systemic inflammatory response and preventing multiple organ dysfunction syndrome (MODS). [Methods] Eighty. SD rats were randomized to control, model, low-dosage (LD) and high-dosage (HD) groups. One day before modeling, HD and LD groups were administered the preparation based on intestine-dredging and Qi-benefiting method by 60g/kg and 30 g/kg for 2 times, and control and model groups were given equal amounts of normal saline. On the 2nd day after the administration, 3 groups except the control group were modeled on the given reference. Twelve hours after modeling, the content of TNF-α and NO in serum was examined and histopathological examination of the main organs was conducted. [Results] Compared with the control group, the level of TNF-α and NO significantly increased (P0.05) in the model group, and compared with the model group, greatly decreased in LD and HD groups (P0.05). But there is no obvious dose-effect relationship. [Conclusion] The preparation based on the intestine-dredging and Qi-benefiting method may inhibit systemic inflammatory response and prevent MODS." @default.
- W2355503883 created "2016-06-24" @default.
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- W2355503883 date "2004-01-01" @default.
- W2355503883 modified "2023-09-25" @default.
- W2355503883 title "Effect of Intestine-Dredging and Qi-Benefiting Method in the Management of Systemic Inflammatory Response and Multiple Organ Dysfunction in Rats" @default.
- W2355503883 hasPublicationYear "2004" @default.
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