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- W2355509695 abstract "Objective To study the modulation of salvia on function of Kupffer cells during acute liver injury.Methods Forty rats were randomly divided into 4 groups,the normal control group,the model group,the gadolinium triehloride (GT) group,and the salvia group.To rats in the latter two groups,GT were given through caudal vein injection for 2 days,and alcohol abstract of salvia was administered additionally to the salvia group by subcutaneous injection.Then rats,except those in the normal control group,thioacetamide (TAA) was give,,by gastrogavage to cause acute liver in jury.Criteria,including phagocytic index (PI),tumor necrosis factor (TNF-α),alanine transaminase (ALT),endotoxin content and total bilirubin (TB) were observed.Results Level of PI was significantly higher and levels of endotoxin, TNF-α,ALT and TB were significantly lower in the salvia group than those in the GT group (P0.05).Conclusion Salvia has the effect of enhancing phagocytic function of Kupffer cell in blocking state and decreasing secretion of inflam- matory mediator TNF-α,to alleviate the liver cell injury." @default.
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- W2355509695 date "2004-01-01" @default.
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- W2355509695 title "Modulatory Effect of Salvia on Kupffer Cell Function during Acute Liver Injury" @default.
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