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- W2355535499 abstract "Objective: Our aim was to observe the reconstruction of desmin during chronic overload cardiac hypertrophy and failure in rats with ascending aortic stenosis. Methods: Animal models of ascending aortic stenosis were made in female Wistar rats .The cardiac myocytes were isolated from left ventrium(LV). The immunofluorescent labeling of isolated myocytes and Western blotting analysis were used. Results: The expression of desmin protein in LV myocytes increased significantly in the group of cardiac hypertrophy and heart failure compared with controls (P0.01). The distribution of desmin filaments didn't change obviously compared with controls. Conclusion: The reconstruction of desmin in LV myocytes plays an important role in the transform of mechanical overload of cardiac hypertrophy to subsequent heart failure." @default.
- W2355535499 created "2016-06-24" @default.
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- W2355535499 date "2003-01-01" @default.
- W2355535499 modified "2023-09-26" @default.
- W2355535499 title "Reconstruction of Desmin During Chronic Pressure Overload Cardiac Hypertrophy and Failure in Rats" @default.
- W2355535499 hasPublicationYear "2003" @default.
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