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- W2355559848 abstract "Objective:To evaluate application value of high performance liquid chromatography(HPLC) in clinical diagnosis of β-thalassemia in Fujian,the results of gene detection were used as gold standard. Methods:308 patients visiting outpatient department of genetic consultation in the hospital from January 2009 to June 2010 were selected,HPLC was used to detect the content of hemoglobin subtype HbA2,and its application value in diagnosis of β-thalassemia was analyzed retrospectively. Results:The results of gene detection were used as gold standard,the sensitivity,specificity,accuracy,positive predictive value and negative predictive value of HPLC in screening of β-thalassemia were 99.2%,96.2%,98.3%,98.4% and 98.1%,respectively. Conclusion:The sensitivity and specificity of HPLC in screening of β-thalassemia are high,HPLC is an ideal method to screen β-thalassemia on a large scale." @default.
- W2355559848 created "2016-06-24" @default.
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- W2355559848 date "2011-01-01" @default.
- W2355559848 modified "2023-09-25" @default.
- W2355559848 title "Exploration on the clinical value of high performance liquid chromatography in detection of β-thalassemia" @default.
- W2355559848 hasPublicationYear "2011" @default.
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