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- W2355573810 abstract "Objective To study the gene distribution of extended-spectrumβ-lactamases(ESBLs) and metallo-β-lactamases(MBLs) in Acinetobacter baumannii in Tianjin area.Methods Totally 72 strains of Acinetobacter baumannii were isolated from six hospitals with the levelⅢof first-class in Tianjin area.Antimicrobial susceptibility testing was performed by the Kirby-Bauer disk diffusion method;MBL phenotype screening was performed by double disc enhancing test for imipenem-resistance Acinetobacter baumannii;IMP-1,IMP-2,VIM-2 genes were detected by PCR;ESBLs phenotype screening was performed by three-dimensional test for the third cephalosporin-resistant Acinetobacter baumannii;ESBLs genes were detected by PCR.Results Four isolates were MBL positive out of 8 strain of imipenem-resistant Acinetobacter baumannii;PCR assay showed 1 isolate expressed IMP-1 gene,and 3 isolates were PCR positive for IMP-1,IMP-2 and VIM-2 MBL.In 30 strains of the third cephalosporin-resistant Acinetobacter baumannii,11 isolates expressed TEM gene,4 isolates expressed PER gene,and 1 strain expressed VEB-1 gene.Conclusion In genotyping of ESBLs in Acinetobacter baumannii,TEM-type is predominant in Tianjin area.IMP-1,IMP-2 and VIM-2 MBL were found in imipenem-resistant Acinetobacter baumannii isolates;furthermore,VEB-1 ESBLs and VIM-2 MBL were firstly reported in Tianjin area." @default.
- W2355573810 created "2016-06-24" @default.
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- W2355573810 date "2009-01-01" @default.
- W2355573810 modified "2023-09-24" @default.
- W2355573810 title "Genotyping of extended-spectrum β-lactamases and metallo-β-lactamases in Acinetobacter baumannii" @default.
- W2355573810 hasPublicationYear "2009" @default.
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