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- W2355592331 abstract "Objective:To investigate the influence of resveratrol on TNF-α and IL-1β level of blood serum in rats with traumatic brain injury and the possible cerebral protection mechanism of resveratrol.Methods: Seventy-five rats were randomly divided into three groups: traumatic group(n=25,no other treatment),control group(n=25,treated with inorganic serum) and treatment group(n=25,treated with resveratrol,50mg/kg,ip).The traumatic brain injury model was induced by Feeney's method.The levels of TNF-α and IL-1β were measured by the method of radioimmunity at the time of 3 h,12 h,24 h,48 h and 72 h after injury.Results:The levels of TNF-α and IL-1β in blood serum decreased significantly in treatment group than that of the control group(P0.05).There was no significant difference between the traumatic group and the control group(P0.05).Conclusion:Resveratrol reduces the levels of TNF-α and IL-1β in blood serum of rats with traumatic brain injury and lessens the inflammatory reaction.Resveratrol has good curative effect on traumatic brain injury." @default.
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- W2355592331 date "2010-01-01" @default.
- W2355592331 modified "2023-09-23" @default.
- W2355592331 title "Eeffects of resveratrol on inflammatory factors of blood serum in rats with traumatic brain injury" @default.
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