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- W2355668549 abstract "Objective To study alteration of expression Gq/11 protein in the small intestine of rats during ALI.Methods To establish an ALI model(OA group) in 40 male healthy wistar rats by intravenous oleic acid.The rats were divided into OA30min,OA60min,OA90min,and OA120min sub-groups.ACE activity was measured.Concentration of Gq/11 of all groups in the small intestine were examined by Western blot.Results With time passing,compared with control group concentration of Gq/11 of OA group respectively increased to(138.91±23.03)%,(143.99±23.01)%,(150.68±26.25)%,(173.05±21.51)%(P0.05 or 0.01).Plasma and small intestine homogenate LDH activity and MDA content of OA group increased(P0.05 or 0.01).Plasma ACE activity was lower than that of C group(P0.01),while small intestine homogenate ACE activity gradually increased with time passing.Conclusion Up regulation of the expression of Gq/11 may play a role in small intestine injury during ALI." @default.
- W2355668549 created "2016-06-24" @default.
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- W2355668549 date "2005-01-01" @default.
- W2355668549 modified "2023-09-28" @default.
- W2355668549 title "The Alteration of Expression Gq/11 Protein in the Small Intestine During Acute Lung Injury" @default.
- W2355668549 hasPublicationYear "2005" @default.
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