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- W2355684978 abstract "Objective The aim of this study was to evaluate the efficacy and toxicity of different dose-schedule FP regiment in the treatment of patients with advanced esophagus cancer.Methods From March 1998 to June 2000,86 cases of advanced esophageal cancer were randomly divided into 3 groups:A (28 cases) B (26 cases) C (32 cases).And they were respectively treated with FP-regimen of different dosage and port of administration.Results The response rates in these groups were 42.86%(12/28),38.47%(10/26) and 40.63%(13/32),respectively.The median remissive times were 2.3,2.5 and 2.2 months,repectively,which was not significantly (P0.05) different.The conditions of relaxation and obstruction were better in Group C than in Group A and B,but is was significantly different.Among these groups,thd toxicity in Group A was the highest.That meant they had nausea,leukopenia and the injury of the kidneys.The patients in Group B also had light nausea and leukopenia.Group C was the lowest.That meant that the patients in it had only nausea.The toxicity in the three groups was significantly different (P0.01).Conclusion FP-regiment of intravenous dripping low dose cisplatin with p.o 5-Fluorouracil for patients with advanced esophagus cancer is an active,practical regimen with relatively low toxicity.And it is especially suitable for elderly patients and the basic hospitals." @default.
- W2355684978 created "2016-06-24" @default.
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- W2355684978 date "2003-01-01" @default.
- W2355684978 modified "2023-09-25" @default.
- W2355684978 title "Clinic Study of Different Dose-schedule FP Regiment in the Treatment of Patients with Advanced Esophagus Cancer" @default.
- W2355684978 hasPublicationYear "2003" @default.
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