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- W2355685671 abstract "Object To explore the relationship between expression of MDR1 gene in human colorectal carcinoma and clinicopathological changes.Methods From September 2004 to July 2006,a total of 93 consecutive patients with colorectal carcinoma were recruited, and MDR1 mRNA were detected by RT-PCR .Fresh tumor tissues were surgically resected without chemotherapy before operation.Results The positive rate of MDR1 mRNA was 37.63%.The MDR1 gene expression was not significantly correlated with age, sex tumor size, histologic types, lymph node involvment or Dukes stage.Conclusion Because of high expressive level of MDR1 gene in untreated colorectal carcinoma, appropriate chemotherapeutic regimen should be individually chosen for colorectal carcinoma. The expression of MDR1 gene in untreated cancer was independent of morphologic prognostic indexes without correlation between MDR1 gene expression and morphological indexes." @default.
- W2355685671 created "2016-06-24" @default.
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- W2355685671 date "2007-01-01" @default.
- W2355685671 modified "2023-09-24" @default.
- W2355685671 title "Clinical singificance of mutidruge resistance gene expression in colorectal carcinoma" @default.
- W2355685671 hasPublicationYear "2007" @default.
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