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- W2355691903 abstract "Objective:To investigate ultrastructural changes of skeletal muscle capillary in tree shrews with insulin resistance induced by feeding on high saccharose and high fatfeed. Methods:The tree shrews were randomly assigned as the chow diet group (group A, 8 animals) and the highsugarhighfatfeeding group(groupB, 11 animals).The latter were fed by turns 1 day interval with the mixfood containing 40% saccharose and 20% fat respectively. The samples of skeletal muscle were taken from quadriceps femoris of the animals following general anesthesia after 29 weeks treatment. Ultrathin sections were cut and observed under electron microscope. Results: The caplillary endothelial surface of skeletal muscle of groug B shown significantly unevenness with projections extend into the capillary lumen accompanied with formation of septa. The pinoeytotie vesicles were increased in the cytoplasm of some endothelial cells. Obvious swollen and hydropic degentration of the endothelial cell with the lumen stenosis were seen. Conclusion:It is obvious that insulin resistance in tree shrews induced by diets could result in markedly changes of the ultrastructure of endothelial cell of the capillary of skeletal muscle. " @default.
- W2355691903 created "2016-06-24" @default.
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- W2355691903 date "2003-01-01" @default.
- W2355691903 modified "2023-09-26" @default.
- W2355691903 title "The ultrapathological observation of skeletal muscle capillary in tree shrews on experimental insulin resistance" @default.
- W2355691903 hasPublicationYear "2003" @default.
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