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- W2355696784 abstract "RING1 can bind to DNA and inhibit some gene transcription.RING1 was identified to interact with lamin A by screening a human skeletal muscle library in a yeast two-hybrid interacting screen.The results of one to one reverse hybridization indicated that AH109 transfected with RING1 and lamin A constructs could grow on SD/-Leu/-Trp/-Ade/-His medium.RING1 was inserted into pEGFP-N1 vector and the constructs including pDsRed-LA and pEGFP-RING1 was used to transfect HEK293 cells.Visualized by laser confocal microscopy,RING1 and Lamin A were co-located around nucleus.Interatcion of RING1 and lamin A was comfirmed by immunoprecipitations.These results showed a new lamin A binding protein that can present some evidence for lamin A acting on gene expression and cell senescence." @default.
- W2355696784 created "2016-06-24" @default.
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- W2355696784 date "2011-01-01" @default.
- W2355696784 modified "2023-09-25" @default.
- W2355696784 title "In vivo Interation of RING1 and Lamin A" @default.
- W2355696784 hasPublicationYear "2011" @default.
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