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- W2355710886 abstract "Objective:To evaluate clinical efficacy and safety of domestic recombinant human erythropoietin (rhEPO) in preventing and treating anemia of pematurity in very low birth weight (VLBW) infants.Methods:Thirty VLBW infants were randomly divided into rhEPO treated group or control group.RhEPO treated group were given domestic rhEPO subcutaneously from one week of life.Control group received no rhEPO.All infants received oral iron or,if necessary,erythrocytes transfusion.Hematologic parameters,transfusion requirements,caloric intake,and growth were monitored.Results:Serum rhEPO levels of treatment group were significantly higher than those in control grop ( P 0.01).Higher levels of hemoglobin (Hb),hematocrit (Hct) and reticulocyte counts (Ret) were found in rhEPO treated group ( P 0.01).Serum ferritin (SF) level was significantly lower in rhEPO treated group compared with control group ( P 0.001).The frequency of transfusions was lower in rhEPO treated group ( P 0.05).The rhEPO treated infants had a greater weihgt gain during therapy ( P 0.05).Conclusion:Domestic rhEPO therapy can effectively elevate the Hb?Hct?Ret level and is safe and efficient in preventing or treating anemia in VLBW infants.No side effect is found relative to rhEPO." @default.
- W2355710886 created "2016-06-24" @default.
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- W2355710886 date "2002-01-01" @default.
- W2355710886 modified "2023-09-25" @default.
- W2355710886 title "Clinical Study of Recombinant Human Erythropoietin in Preventing and Treating Anemia of Prematurity in Very Low Birth Weight Infants" @default.
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