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- W2355720688 abstract "Objective To investigate TNF-α expression at different time points in the brain of rats with cerebral ischemia-reperfusion(IR) injury,in order to discuss the mechanism of eye-acupuncture therapy and observe the intervention effects on the hippocampus.Methods Healthy SD rats,male and female,were randomly divided into normal,sham-operated control,model and eye-acupuncture groups.Sham-operated control,model and eye-acupuncture groups were divided into 3,24 and 72 h subgroups.The rat model of cerebral IR was established by suture method.Eye acupoint liver area,kidney area,upper jiao area and lower jiao area were selected and acupunctured horizontally,inserting needle in 3 mm deep,retaining needle for 20 min.All the animals were executed respectively at 3,24,72 h after reperfusion and draw materials.The method of immunohistochemistry and Western blot technology were taken to detect the changes of hippocampus TNF-α expression in rats after the eye-acupuncture therapy.Results Compared with that of model group,TNF-α expression in the hippocampus of rats of the eye-acupuncture group was significantly decreased obviously at 3,24,72 h after reperfusion.Conclusions The eye-acupuncture therapy could down-regulate hippocampus TNF-α expression in rats with cerebral IR injury,suppress inflammatory response induced by cerebral IR and play a role in protecting brain." @default.
- W2355720688 created "2016-06-24" @default.
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- W2355720688 date "2012-01-01" @default.
- W2355720688 modified "2023-09-25" @default.
- W2355720688 title "The effect of eye acupuncture therapy on the expression of TNF-α of hippocampus at different time points in rats with cerebral ischemia reperfusion" @default.
- W2355720688 hasPublicationYear "2012" @default.
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