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- W2355726854 abstract "Objective:To study the correlation of expression of mutant p53 gene with histological grade,metastasis and tumor size or cover producing of hepatocellular carcinoma(HCC).Methods:p53 protein expression in the cancer tissue and peri-cancer tissue samples of the 41 cases patients with HCC were detected by the immunocytochemical method(SP),to study the correlation of expression of mutant p53 gene with histological grade,Metastasis and tumor size or cover producing of hepatocellular carcinoma(HCC).Results:The positive rates of p53 proteins in the cancer tissue and peri-cancer tissue samples were respectively 43.9% and 4.9%.The difference between them was significant(P0.01).For positive rates of p53,Ⅲ~Ⅳ grade HCC was obviously higher thanⅠ~Ⅱgrade,HCC with blood or lymphatic metastasis was higher than without blood or lymphatic metastasis,the difference between them was significant(P0.05).But there wasn't correlation between expression of p53 protein expression with tumor size or cover producing of HCC.Conclusion:There were visible correlation between mutant p53 gene with histological grade,metastasis.But there weren't correlation between mutant p53 gene with tumor size or cover producing of HCC." @default.
- W2355726854 created "2016-06-24" @default.
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- W2355726854 date "2008-01-01" @default.
- W2355726854 modified "2023-09-23" @default.
- W2355726854 title "Correlation of expression of mutant p53 gene with histological grade,metastasis and tumor size or cover producing of hepatocellular carcinoma" @default.
- W2355726854 hasPublicationYear "2008" @default.
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