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- W2355729517 abstract "Objective: To establish a reliable rat model of orthotopic liver transplantation with well perfusion, shortened anhepatic phase and hepatic artery reconstruction in transplanted liver. Methods: The model was established with modified cuff technique. The donor liver was cold perfused through abdominal aorta and portal vein respectively, the liver of recipient was step-excised, the suprahepatic vena cave(VC)was sutured end -to -end with 8-0 nylon line, and the continuity of infrahepatic VC and portal vein(PV)were established by means of cuff method respectively. The blood supply of hepatic artery of the recipient rat was reconstructed by a modified arterial sleeve anastomosis and the anastomosis of the common bile duct was performed with an internal stent. Results: There were 76 liver transplantations performed with hepatic artery reconstruction. The 24h and one week survival rate after operation was 93.4% and 86.8% respectively. Conclusions: It is important for successful operation with sophisticated microsurgical technique, effectively modified measure and attention for operation details. Well perfusion, shortened anhepatic phase of recipient and hepatic artery reconstruction in transplanted liver can increase the stability of animal model." @default.
- W2355729517 created "2016-06-24" @default.
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- W2355729517 date "2006-01-01" @default.
- W2355729517 modified "2023-09-26" @default.
- W2355729517 title "Establishment of rat model of two-cuff method liver transplantation with dual perfusion and blood supply of hepatic artery" @default.
- W2355729517 hasPublicationYear "2006" @default.
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