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- W2355751492 abstract "OBJECTIVE To analyse the relation between serum clozapine level and its efficacy or side effects.METHODS The serum clozapine level was determined by HPLC.The efficacy and side effects of clozapine were measured by BPRS and TESS.Decision analysis was used to study the relationship between serum clozapine level and the efficacy or side effects.RESULTS The efficacy of clozapine was best when the serum clozapine levels were over the range of 200～600 μg·L -1 ,the mild side effect was found when the serum clozapine levels were over 400 μg·L -1 .CONCLUSION It was suggested that the appropriate serum clozapine level should be controlled within 200～500 μg·L -1 ." @default.
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- W2355751492 date "2002-01-01" @default.
- W2355751492 modified "2023-09-25" @default.
- W2355751492 title "The application of decision analysis to the TDM of clozapine" @default.
- W2355751492 hasPublicationYear "2002" @default.
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