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- W2355754614 abstract "AIM: To observe and compare the efficacies between diltiazem and nifedipine on declining blood pressure and heart rate in patients of hypertension with high heart rates. METHODS:Diltiazem group(group D) of 37 patients(M 21, F 16; age 50 a± s 11 a) received diltiazem SR 180 mg, po , qd for 4wk. Nifedipine group(group N) of 38 patients(M 23, F 15; age 51 a±10 a) received nifedipine CR 20 mg, po , bid for 4 wk. RESULTS:Blood pressure was declined obviously in both two groups after treament( P 0.01). SBP declined from(22.7±1.6) kPa to (18.0±1.3) kPa in group D; but from (23.8±1.5) kPa to (17.6±1.3) kPa in group N. The latter appeared superior to the former ( P 0.05 ). DBP declined from (12.7±1.3) kPa to (10.4± 1.5 ) kPa in group D, which appeared superior to that of group N [from (12.8±1.6) kPa to (10.8±2.3) kPa) ( P 0.05)]. Heart rate declined from (90±10)·min -1 to (71±8)beat·min -1 in group D( P 0.01 ), but which was still (93±8)beat·min -1 in group N. There was a significant difference between two groups( P 0.01). CONCLUSION: Diltiazem has efficacies both in decling BP and HR. It is superior to nifedipine on the treatment of patients of hyperthension with high heart rate." @default.
- W2355754614 created "2016-06-24" @default.
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- W2355754614 date "2001-01-01" @default.
- W2355754614 modified "2023-09-25" @default.
- W2355754614 title "Diltiazem-sustained released tablet vs nifedipine-controlled released tablet in treating essential hypertension with high heart rate" @default.
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