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- W2355758623 abstract "To investigate the effect of daily melatonin supplementation on metabolism of intra-abdominal adipose tissue of rat. Twenty-four SD rats were divided into 3 groups randomly (n=8) including high-dose melatonin (10 mg·kg~(-1)·d~(-1)), low-dose melatonin (0. 2 mg·kg~(-1)·d~(-1)) and control (saline containing 2% ethanol) groups. The rats of each group were fed for 3 weeks, then the concentrations of plasma triglyceride (TG), leptin and insulin were measured. The body weight and the mass of retroperitoeal fat mass were significantly decreased in high-dose melatonin group compared with those in control and low-dose melatonin groups (P<0.01). The concentration of plasma leptin was significantly lower in high-dose melatonin group than in control and low-dose melatonin groups (P<0.05). The concentrations of plasma insulin and TG were not significantly different between groups. It is suggested that administration of high-dose can reduce intraabdominal fat mass and decrease the concentration of plasma leptin." @default.
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- W2355758623 date "2005-01-01" @default.
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- W2355758623 title "Effect of melatonin on metabolism of intra-abdominal fat of rat" @default.
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