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- W2355816092 abstract "Objective To explore the protective effects of mild hypothermic cardiopulmonary bypass(CPB) on the myocardium of beating heart.Methods 50 patients undergoing valve replacement were randomly divided into an experimental group (beating heart group) and a control group (cold cardioplegic arrest heart group), with 25 patients each.The blood was sampled 5 min before CPB,at 2,6,24 and 48h during CPB,and after CPB for the measurements of creatine phosphokinase (CK),creatine phosphokinase isoenzyme(CK-MB),lactic dehydrogenase(LDH),aspartate amino transferase(AST).The myocardial tissues were taken from the right atrium for assessing ultrastructural changes.Results After reperfusion,the levels of CK,CK-MB,LDH and AST were significantly higher in control group than those in experimental group (P0.01),and myocardial ultrastrctural changes were significant in control group. Conclusion The activities of serum CK,CK-MB,LDH and AST are effectively depressed in valve replacement with beating heart under mild hypothermic CPB,which may decrease myocardal ischemia-reperfusion injury." @default.
- W2355816092 created "2016-06-24" @default.
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- W2355816092 date "2005-01-01" @default.
- W2355816092 modified "2023-09-22" @default.
- W2355816092 title "Changes of myocardial enzymes and ultrastructure in patients undergoing beating heart valve replacement under mild hypothermic cardiopulmonary bypass" @default.
- W2355816092 hasPublicationYear "2005" @default.
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