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- W2355821987 abstract "Objective To investigate the expression of RECK and MMP-2 protein and their correlations with the occurrence,development,invasion and metastasis of oral squamous cell carcinoma. Methods SP immunohistochemistry method was used to detect the expression of RECK and MMP-2 protein in 68 cases of oral squamous cell carcinoma and 68 cases of oral mucosa. Statistical analysis was performed using chi-square test. Results The protein expression of RECK and MMP-2 were closely correlated with the tumor grade, infiltration and lymph node metastasis in oral squamous cell carcinoma(all P 0.05). The expression rate of RECK protein was increased in tumor and the oral mucosa, which was 40.4% and 83.8%, respectively, and there was significant difference between every two groups(P 0.01);however, the expression rate of MMP-2 protein was decreased in tumor and the oral mucosa, which was 76.5%,27.9%, respectively, and there was significant difference between every two groups (P 0.01). Conclusion RECK and MMP-2 may play important roles in the infiltration and metastasis of mucosal epithelium in oral squamous cell carcinoma. United detection of RECK and MMP-2 can be used in the early diagnosis and prognosis judgement of oral squamous cell carcinoma." @default.
- W2355821987 created "2016-06-24" @default.
- W2355821987 creator A5001220537 @default.
- W2355821987 date "2010-01-01" @default.
- W2355821987 modified "2023-09-26" @default.
- W2355821987 title "Expression of RECK and MMP-2 in oral squamous cell carcinoma and its correlation with cancer invasion and metastasis." @default.
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