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- W2355823613 abstract "Objective To investigate therapeutic effect of pulmonary delivery of hemocoagulase on acute lung hemorrhage induced by lipopolysaccharide in neonatal rats.Methods Healthy neonatal Sprague-Dawley rats were ramdomly divided into 5 groups:control,Hemorrhage,Lipopolysaccharidee group,LPS+ pulmonary delivery of hemocoagulas group,LPS + venous delivery of hemocoagulas group,The changes of bleeding time(BT),coagulation time(CT),prothrombin time(PT)and fibrinogen were measured.All changes were observed at 1 h,2 h and 4 h after delivery of hemocoagulase.Results Compared with Lipopolysaccharide group,the lung hemorrahage was evidently ameliorated after pulmonary delivery of hemocoagulase.Bleeding time,coagulation time and prothrombin time was shortened.Conclusion Pulmonary delivery of hemocoagulase can shorten bleeding time and coagulation time of rats with acute lung hemorrhage." @default.
- W2355823613 created "2016-06-24" @default.
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- W2355823613 date "2009-01-01" @default.
- W2355823613 modified "2023-09-23" @default.
- W2355823613 title "Therapeutic Effect of Pulmonary Delivery of Hemocoagulase on Acute Lung Hemorrhage Induced by Lipopolysaccharide in Neonatal Rats" @default.
- W2355823613 hasPublicationYear "2009" @default.
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