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- W2355833674 abstract "Objective:To study the relationship between coronary risk factors of diabetes mellitus(DM)and the severity of coronary artery stenosis(CAS)in patients with coronary artery disease .Methods:Admitted patients with suspected coronary artery disease(CAD)were studied and were divided into 2 subgroup as DM CAD group ( n =66) and nonDM CAD group ( n =148). All the patients underwent selective coronary angiography, survey of smoking, blood pressure, DM and examination of blood glucose,lipid,lipoprotein and apolipoprotein during the hospitalization.The severity of CAS was quantified in a modified Gensini score. Subsequently,the relationship between diabetes mellitus such as lipid as coronary risk factors and the severity of CAS was anlyzed.Results:The course of DM and coronary artery Gensini score were significantly higher in DM CAD group than that in nonDM CAD group( P 0.05).Compared with nonDM CAD group, the blood glucose, serum total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL C) and apolipoprotein B (apoB) were higher in DM CAD group, while high density lipoprotein cholesterol (HDL C), apolipoprotein A 1 (apo A 1) were lower ( P 0.01 or P 0.05).A significant positive correlation (γ=0.379～0.484, P 0.01)of the severity of CAS to age,the course of DM, TG, LDL C and apoB was found on the basis of the correlation analysis. The negative correlation of CAS severity and HDL C, apoA 1 (γ=-0.356～-0.330, P 0.01) was also observed.Multiple regression analysis indicated that the course of DM, TC, TG and LDLC were positively correlated to CAS, but HDL C and apoA 1 were negatively related to CAS.Conclusion:The severity of CAS was more serious in coronary artery disease patients with DM.Age,the course of DM and their blood lipid such as TC,TG and lipoprotein (LDL C and HDL C) play very important role in coronary artery stenosis." @default.
- W2355833674 created "2016-06-24" @default.
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- W2355833674 date "2002-01-01" @default.
- W2355833674 modified "2023-09-26" @default.
- W2355833674 title "Relationship between diabetes mellitus and severity of coronary artery stenosis in patients with coronary artery disease" @default.
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