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- W2355848060 abstract "Objective To discuss the level of expression of nm23, a metastasis suppressing gene and TGFβ 1 gene in human non small cell lung cancer, as well as its clinical and pathological correlation.Methods We investigated, at the level of protein synthesis the expression of the metastasis suppressing gene nm23 and TGF β 1 gene in the tissues of 83 human NSCLC specimens, by means of immunohistochemistry.Results The expression level of nm23 and TGFβ 1is closely correlated to TNM staging degree of differentiation, and metastasis of lung cancers( P 0.05).Primary lung cancer with metastasis to lumph nodes has a significantly lower expression level of TGFβ 1 than those without such metastasis( P 0.05).Conclusion Both nm23 and TGF β 1 take part in the regulation of the process of the process of the genesis, development, and metastasis of lung cancer. A simultaneous decrease in the expression of both genes suggests metastasis and a poor prognosis." @default.
- W2355848060 created "2016-06-24" @default.
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- W2355848060 date "2001-01-01" @default.
- W2355848060 modified "2023-09-24" @default.
- W2355848060 title "A Discussion on the Expression of nm23 and TGF β_1 in Human Non-Small Cell Lung Cancer and Its Clinical and Pathological Correlation." @default.
- W2355848060 hasPublicationYear "2001" @default.
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