Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355856211> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2355856211 abstract "AIM: To investigate the expression of peroxisome proliferator-activated receptors (PPARs) in human endothelial cells, and their effects on plasminogen activator inhibitor-1 transcription. METHODS: The expression of three types of PPARs in mRNA level were detected in human umbilical vein endothelial cells(HUVECs) by using RT-PCR. Cultured endothelial cells line-ECV304 were transfected with PAI-1 promoter controlling CAT reporter gene and co-transfected with varying doses (250, 500, 1 000 ng) of expression vectors PPARα or PPARγ.The transcripton activity of PAI-1 promoter were detected with ELISA. RESULTS: There were all three types of PPARs mRNA expression in HUVECs, while the expression of PPARγ was less than that of PPARα( P 0.01)and PPARδ( P 0.01). Enhancing expression level of PPARα induced the transcription activity of PAI-1 promoter in a dose-dependent manner, and there was no effect in enhancing expression of PPARγ. CONCLUSION: There were all three types of PPARs mRNA expression in endothelium; PPARα acted in the induction of PAI-1 transcription in endothelial cells." @default.
- W2355856211 created "2016-06-24" @default.
- W2355856211 creator A5026199458 @default.
- W2355856211 date "2003-01-01" @default.
- W2355856211 modified "2023-09-25" @default.
- W2355856211 title "The influence of peroxisome proliferator-activated receptors on transcription of plasminogen activator inhibitor-1 in endothelial cells" @default.
- W2355856211 hasPublicationYear "2003" @default.
- W2355856211 type Work @default.
- W2355856211 sameAs 2355856211 @default.
- W2355856211 citedByCount "0" @default.
- W2355856211 crossrefType "journal-article" @default.
- W2355856211 hasAuthorship W2355856211A5026199458 @default.
- W2355856211 hasConcept C101762097 @default.
- W2355856211 hasConcept C104317684 @default.
- W2355856211 hasConcept C132376346 @default.
- W2355856211 hasConcept C134018914 @default.
- W2355856211 hasConcept C150194340 @default.
- W2355856211 hasConcept C153911025 @default.
- W2355856211 hasConcept C170493617 @default.
- W2355856211 hasConcept C185592680 @default.
- W2355856211 hasConcept C187345961 @default.
- W2355856211 hasConcept C202751555 @default.
- W2355856211 hasConcept C2776992346 @default.
- W2355856211 hasConcept C2777411675 @default.
- W2355856211 hasConcept C2779679481 @default.
- W2355856211 hasConcept C2780675426 @default.
- W2355856211 hasConcept C54009773 @default.
- W2355856211 hasConcept C54355233 @default.
- W2355856211 hasConcept C55493867 @default.
- W2355856211 hasConcept C81885089 @default.
- W2355856211 hasConcept C86339819 @default.
- W2355856211 hasConcept C86803240 @default.
- W2355856211 hasConcept C88045685 @default.
- W2355856211 hasConceptScore W2355856211C101762097 @default.
- W2355856211 hasConceptScore W2355856211C104317684 @default.
- W2355856211 hasConceptScore W2355856211C132376346 @default.
- W2355856211 hasConceptScore W2355856211C134018914 @default.
- W2355856211 hasConceptScore W2355856211C150194340 @default.
- W2355856211 hasConceptScore W2355856211C153911025 @default.
- W2355856211 hasConceptScore W2355856211C170493617 @default.
- W2355856211 hasConceptScore W2355856211C185592680 @default.
- W2355856211 hasConceptScore W2355856211C187345961 @default.
- W2355856211 hasConceptScore W2355856211C202751555 @default.
- W2355856211 hasConceptScore W2355856211C2776992346 @default.
- W2355856211 hasConceptScore W2355856211C2777411675 @default.
- W2355856211 hasConceptScore W2355856211C2779679481 @default.
- W2355856211 hasConceptScore W2355856211C2780675426 @default.
- W2355856211 hasConceptScore W2355856211C54009773 @default.
- W2355856211 hasConceptScore W2355856211C54355233 @default.
- W2355856211 hasConceptScore W2355856211C55493867 @default.
- W2355856211 hasConceptScore W2355856211C81885089 @default.
- W2355856211 hasConceptScore W2355856211C86339819 @default.
- W2355856211 hasConceptScore W2355856211C86803240 @default.
- W2355856211 hasConceptScore W2355856211C88045685 @default.
- W2355856211 hasLocation W23558562111 @default.
- W2355856211 hasOpenAccess W2355856211 @default.
- W2355856211 hasPrimaryLocation W23558562111 @default.
- W2355856211 hasRelatedWork W1244277802 @default.
- W2355856211 hasRelatedWork W1964083256 @default.
- W2355856211 hasRelatedWork W1978736810 @default.
- W2355856211 hasRelatedWork W1992337083 @default.
- W2355856211 hasRelatedWork W2014277844 @default.
- W2355856211 hasRelatedWork W2039183296 @default.
- W2355856211 hasRelatedWork W2045908562 @default.
- W2355856211 hasRelatedWork W2050409528 @default.
- W2355856211 hasRelatedWork W2052473036 @default.
- W2355856211 hasRelatedWork W2347576041 @default.
- W2355856211 hasRelatedWork W2350011955 @default.
- W2355856211 hasRelatedWork W2357008166 @default.
- W2355856211 hasRelatedWork W2361034620 @default.
- W2355856211 hasRelatedWork W2374859209 @default.
- W2355856211 hasRelatedWork W2391454620 @default.
- W2355856211 hasRelatedWork W2885435066 @default.
- W2355856211 hasRelatedWork W2886849887 @default.
- W2355856211 hasRelatedWork W962393923 @default.
- W2355856211 hasRelatedWork W2904415784 @default.
- W2355856211 hasRelatedWork W2941344433 @default.
- W2355856211 isParatext "false" @default.
- W2355856211 isRetracted "false" @default.
- W2355856211 magId "2355856211" @default.
- W2355856211 workType "article" @default.