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- W2355862031 abstract "OBJECTIVE:To evaluate the curative effect and toxicity of conventional fractionation radiotherapy (CFR) plus concurrent chemotherapy (CFR+C) with CBP on advanced esophageal carcinoma. METHODS:A total of 180 patients with advanced squamous carcinoma of esophagus were randomized into two groups (90 patients per group): Group 1. CFR group, patients were irradiated with 2.0 Gy/f , 5 times a week, to a total dose of 60 Gy; Group 2. CFR+C group, patients were given the same radiation schedual as the CFR group. On Day 1-5 and Day 22-26 of their radiotherapy courses, CBP was delivered intravenously, at the dose of 100 mg/d after irradiation. RESULTS: For the CFR and CFR+C groups, the complete response rates were 52.2% and 36.7% respectively (P0.05), significantly improving the short treatment effects. The 5-,10-year survival rates of CFR and CFR+C were 22.2%,14.4% and 10%,6.7% respectively, P 0.05. More acute toxicities were observed in the CFR+C group, however, they were tolerated by all the patients.CONCLUSIONS: CFR plus concurrent chemotherapy with CBP can significantly improve the short treatment effects and the survival rates of the patients with esophageal carcinoma. More acute toxicities were observed in the CFR+C, however, they could be tolerated by all the patients." @default.
- W2355862031 created "2016-06-24" @default.
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- W2355862031 date "2005-01-01" @default.
- W2355862031 modified "2023-09-23" @default.
- W2355862031 title "Conventional fractionation radiotherapy plus concurrent chemotherapy with CBP on esophageal carcinoma" @default.
- W2355862031 hasPublicationYear "2005" @default.
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