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- W2355878894 abstract "Objective To investigate the clinical and epidemiological features of epidemic cerebrospinal meningitis in recent 8 years in Quxian County,and to guide prevention and cure of this disease.Methods The clinical data of 97 hospitalized patients with epidemic cerebrospinal meningitis from 2000 to 2008 was retrospectively analyzed,and Chi-square test was used for statistical analysis.Results The majority of these 97 patients were juveniles(43 cases,44.6%) and adults(34 cases,35.4%),while the infant patients accounted for a small percentage,only 6.2%(6 cases).In clinical classification,common type was dominant(72.3%),followed by fulminant type(27.7%).Seven cases(7.7%) ended with death.Totally 49 strains of Neisseria meningitides were isolated,with positive culture rate of 50.8%(49/97).The positive rate of blood culture was 44.6%(43/97) and that of cerebrospinal fluid culture was 31.4%(30/97).Drug susceptibility test results showed that Neisseria meningitidis isolates were still highly sensitive to penicillin,ceftriaxone and cefotaxime.However,the resistance rates of the strains to trimethoprim-sulfamethoxazole,gentamycin and ciprofloxacin were all above 80%.Results of serological typing revealed that 82.8%(80/97) cases were infected by group C Neisseria meningitidis.There were more severe cases and higher death rate in patients infected by group C Neisseria meningitidis.The pathogenetic condition of group C Neisseria meningitides infected patients was severe,with a high case fatality.Conclusion Serogroup C Neisseria meningitides has become the preponderant strain in Quxian County.Most of patients infected by group C are juveniles and adults.Penicillin and the third generation cephalosporins are still highly active against Neisseria meningitidis." @default.
- W2355878894 created "2016-06-24" @default.
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- W2355878894 date "2008-01-01" @default.
- W2355878894 modified "2023-09-23" @default.
- W2355878894 title "Clinical and epidemiological analysis of 97 cases of epidemic cerebrospinal meningitis" @default.
- W2355878894 hasPublicationYear "2008" @default.
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