Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355904988> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2355904988 abstract "To detect the programmed cell death (PCD) in embryoid bodies (EBs) derived from mouse embryonic stem cell differentiation in vitro.Undifferentiated ES cells were incubated and differentiate into EBs by hanging drop and suspension culture method. The expression of the primitive endoderm, primitive ectoderm, mesoderm, and visceral endoderm molecules was examined in embryoid bodies by RT-PCR. Apoptotic was confirmed by TUNEL staining,electro microscopy,confocal microscopy,and Western blotting.Four molecular markers were expressed in the EBs.The cavitation and PCD were detected in the development of EBs by TUNEL staining and electron microscopy.Membrane Potential (ΔΨ m) was decreased,and the cleaved-caspases3 as well as cleaved-caspase8 were activated during the development of EBs.These results demonstrated that EBs could be used to study the development of early embryo and that mitochondria play an important role in the PCD of EBs.The system of mouse ES cells differentiated into EBs in vitro provided genetic evidence to investigate PCD and relevant signaling molecules in the early developmental statge of mouse embryo." @default.
- W2355904988 created "2016-06-24" @default.
- W2355904988 creator A5083234708 @default.
- W2355904988 date "2004-01-01" @default.
- W2355904988 modified "2023-09-25" @default.
- W2355904988 title "Programmed Cell Death of Embryoid Body During the Differentiation of Mouse Embryonic Stem Cells" @default.
- W2355904988 hasPublicationYear "2004" @default.
- W2355904988 type Work @default.
- W2355904988 sameAs 2355904988 @default.
- W2355904988 citedByCount "0" @default.
- W2355904988 crossrefType "journal-article" @default.
- W2355904988 hasAuthorship W2355904988A5083234708 @default.
- W2355904988 hasConcept C104317684 @default.
- W2355904988 hasConcept C143948831 @default.
- W2355904988 hasConcept C145103041 @default.
- W2355904988 hasConcept C148738053 @default.
- W2355904988 hasConcept C153911025 @default.
- W2355904988 hasConcept C196843134 @default.
- W2355904988 hasConcept C20875687 @default.
- W2355904988 hasConcept C2777164004 @default.
- W2355904988 hasConcept C2779329299 @default.
- W2355904988 hasConcept C28328180 @default.
- W2355904988 hasConcept C54355233 @default.
- W2355904988 hasConcept C86803240 @default.
- W2355904988 hasConcept C87073359 @default.
- W2355904988 hasConcept C95444343 @default.
- W2355904988 hasConceptScore W2355904988C104317684 @default.
- W2355904988 hasConceptScore W2355904988C143948831 @default.
- W2355904988 hasConceptScore W2355904988C145103041 @default.
- W2355904988 hasConceptScore W2355904988C148738053 @default.
- W2355904988 hasConceptScore W2355904988C153911025 @default.
- W2355904988 hasConceptScore W2355904988C196843134 @default.
- W2355904988 hasConceptScore W2355904988C20875687 @default.
- W2355904988 hasConceptScore W2355904988C2777164004 @default.
- W2355904988 hasConceptScore W2355904988C2779329299 @default.
- W2355904988 hasConceptScore W2355904988C28328180 @default.
- W2355904988 hasConceptScore W2355904988C54355233 @default.
- W2355904988 hasConceptScore W2355904988C86803240 @default.
- W2355904988 hasConceptScore W2355904988C87073359 @default.
- W2355904988 hasConceptScore W2355904988C95444343 @default.
- W2355904988 hasLocation W23559049881 @default.
- W2355904988 hasOpenAccess W2355904988 @default.
- W2355904988 hasPrimaryLocation W23559049881 @default.
- W2355904988 hasRelatedWork W1042592497 @default.
- W2355904988 hasRelatedWork W1577806224 @default.
- W2355904988 hasRelatedWork W1603508604 @default.
- W2355904988 hasRelatedWork W1720754255 @default.
- W2355904988 hasRelatedWork W1984711934 @default.
- W2355904988 hasRelatedWork W2053019739 @default.
- W2355904988 hasRelatedWork W2053536783 @default.
- W2355904988 hasRelatedWork W2061638084 @default.
- W2355904988 hasRelatedWork W2064676889 @default.
- W2355904988 hasRelatedWork W2093582519 @default.
- W2355904988 hasRelatedWork W2159228111 @default.
- W2355904988 hasRelatedWork W2175475483 @default.
- W2355904988 hasRelatedWork W2369260350 @default.
- W2355904988 hasRelatedWork W2387494959 @default.
- W2355904988 hasRelatedWork W2391053044 @default.
- W2355904988 hasRelatedWork W2394017403 @default.
- W2355904988 hasRelatedWork W2406466138 @default.
- W2355904988 hasRelatedWork W2410781457 @default.
- W2355904988 hasRelatedWork W2606170695 @default.
- W2355904988 hasRelatedWork W343897009 @default.
- W2355904988 isParatext "false" @default.
- W2355904988 isRetracted "false" @default.
- W2355904988 magId "2355904988" @default.
- W2355904988 workType "article" @default.