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- W2355935571 abstract "Objective To investigate the clinical characteristics of disseminated penicilliosis marneffei(DPSM) in AIDS patients.Methods Clinical manifestations and laboratory data of 36 patients with DPSM treated in our hospital from January 2010 to February 2014 were retrospectively analyzed.Results Young adults accounted for the majority.Fever occurred in 35 patients(97.2%),cough in 30 patients(83.3%),anemia in 32 patients(88.9%),weight loss in 21 patients(58.3%),rash in 17 patients(47.2%),abdominal pain in 16 patients(44.4%),and swollen lymph nodes in 14 patients(38.9%).Blood culture of all the patients was positive for Penicillium marneffei,and bone marrow culture positive in 9 patients(25.0%).Two patients received amphotericin B alone,11 patients received amphotericin B and then switched to itraconazole,1 patient received voriconazole and men switched to itraconazole,14 patients received itraconazole alone,and 8 patients received fluconazole alone.Seventeen patients(47.2%) were improved and discharged,11 patients(30.6%) were discharged without recovery,and 8 patients(22.2%) died.Conclusions The clinical manifestations of AIDS patients with DPSM are complex and this complication may develop rapidly.Early diagnosis and timely treatment can alleviate or cure DPSM effectively." @default.
- W2355935571 created "2016-06-24" @default.
- W2355935571 creator A5002458667 @default.
- W2355935571 date "2015-01-01" @default.
- W2355935571 modified "2023-09-25" @default.
- W2355935571 title "Clinical analysis of 36 AIDS patients with disseminated penicilliosis marneffei" @default.
- W2355935571 hasPublicationYear "2015" @default.
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