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- W2355939104 abstract "Objective It is to realize the distribution of transforming growth factor-β 1 (TGF-β 1) in polyp tissue and to discuss the effect of TGF-β 1 in the occurrence and development course of nasal polyp. Methods The study object were 84 cases in which there were 65 cases with nasal polyp, 12 cases with chronic nasal sinusitis and seven cases with normal nasal mucous membrane. The expression of TGF-β 1 was detected with immune histochemistry methods. Results The expression of TGF-β 1 was Ⅲ to Ⅳ grades in most of the polyps (55/65), that was Ⅱ to Ⅲ grades in 11 cases with nasal sinusitis and that was Ⅱ grades in normal nasal mucous membrane. There was significant difference between random two groups in the three groups (P0.05). Mass cell, plasma cell, eosinophil, epith epithelial cell and fibroblast were the main staining cells of TGF-β 1. Conclusion Both eosinophil accretion and plasma cell infiltration are the characters of polyp. TGF-β 1 is produced by inflammatory cell and structure cell in polyp. It takes part in the occurrence and development of polyp. Especially, it has important effect in the formation of gland polyp and fibrous polyp." @default.
- W2355939104 created "2016-06-24" @default.
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- W2355939104 date "2003-01-01" @default.
- W2355939104 modified "2023-09-27" @default.
- W2355939104 title "Expression and its sense of transforming growth factor-β_1 in nasal polyp" @default.
- W2355939104 hasPublicationYear "2003" @default.
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