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- W2355946526 abstract "Objective: To study the protective effect of propofol on pulmonary function in cardiopulmonary bypass (CPB). Methods: Thirty cardiac valve replacement patients were randomly divided into two groups including propofol group (group P) and control group (group C). Propofol was given intravenously by 1 mg/kg before CPB followed by 4-6 mg/(kg·h) during operation in group P. Midazolam 0.1-0.2 mg/kg and droperidol 0.1-0.2 mg/kg were infused during CPB in group C. PAWpeak, Cc, MPAP, PVRI, PaO2/FiO2 , p(A-a)(O2) and Qs/Qt were measured and calculated at the time of before CPB, after CPB and the end of operation. Results: PAWpeak, MPAP, PVRI, p(A-a)(O2) and Qs/Qt decreased and PaO2/FiO2 and Cc increased in group P compared with those in group C after CPB. There was significant difference between two groups (P 0.05). At the end of operation all the indexes except PAWpeak and PaO2/FiO2 were significant difference between two groups (P 0.05). Conclusion: Propofol plays protective role on pulmonary injury during CPB." @default.
- W2355946526 created "2016-06-24" @default.
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- W2355946526 date "2005-01-01" @default.
- W2355946526 modified "2023-09-23" @default.
- W2355946526 title "Study on the Effects of Propofol on Pulmonary Function in Cardiopulmonary Bypass" @default.
- W2355946526 hasPublicationYear "2005" @default.
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