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- W2355950003 abstract "Objective: To probe into human papillomavirus (HPV) types and their correlation with cell mediated immunity in patients with condyloma acuminatum (CA) Methods: Polymerase chain reaction (PCR) was employed to detect HPV DNA in tissues Flow cytometer was used to test T cell subpopulation in peripheral blood and ELISA method to examine interleukin 12(IL-12) in serum Results: HPV DNA was detected in 96 20% of CA tissues and 5% of pseudocondyloma of vulvae (PCV) tissues The CA patients showed lower levels of CD3 +T cell, CD4 + T-cell, CD4 +/CD8 + T cell ratio, which were(51 23±5 51)%, (23 52±4 90)%, 0 90±0 84 respectively, than those of the PCA patients, which were (60 31±9 46)%, (35 13±5 94)%, 1 55±0 77, and those of the healthy people, which were (61 01±9 21)%, (36 46±6 04)%, 1 59±0 78(P0 01) The level of CD8 + T cell of the CA was (25 98±5 78)%, which was higher than that of the PCV (22 67±2 94)% and that of the healthy (22 86±3 01)%(P0 05) IL-12 level of the CA (61 38±5 38)% was lower than that of the PCV (82 03±9 01)% and that of the healthy (81 75±10 18)%(P0 05) T cell subpopulation and IL-12 level in CA patients with different HPV types were similar (P0 05) Conclusion: Cellular immunodeficiency exists but is similar in CA patients with different HPV types" @default.
- W2355950003 created "2016-06-24" @default.
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- W2355950003 date "2002-01-01" @default.
- W2355950003 modified "2023-09-23" @default.
- W2355950003 title "Human papillomavirus type and the relation with cell-mediated immunity in patients with condyloma acuminatum" @default.
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