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- W2355969766 abstract "Objective To explore the feasibility of mitoxantrone (MTZ) plus cytarabine (Ara-C) (MA regimen) as the first line therapy in the induction treatment of previously untreated patients with acute myeloid leukemia (AML).Methods Retrospective studying the efficacy and toxicity of previously untreated patients with AML who treated with MA regimen and daunorubicin (DNR) or harringtonine (HT) plus Ara-C (DA/HA regimen).Results In MA regimen and DA/HA regimen, the complete remission (CR) rates were 52.5% and 30.4%(P=0.090), respectively. The death rates in the induction therapy period were 7.5% and 8.7% (P0.05), respectively. In MA regimen WBC depression was more serious than that in DA/HA regimen (P0.05), but no significant differences were found in Hb, PLT depression or the incidence and severity of side effects (P0.05).Conclusion The complete remission (CR) rate is higher in MA regimen than that in DA/HA regimen, but no significant differences are found in side effects between two regimens. MA regimen is recommended as one of the first line therapy in the induction treatment of previously untreated patients with AML." @default.
- W2355969766 created "2016-06-24" @default.
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- W2355969766 date "2005-01-01" @default.
- W2355969766 modified "2023-09-24" @default.
- W2355969766 title "Efficacy analysis of mitoxantrone plus cytarabine regimen in the induction treatment of previously untreated patients with acute myeloid leukemia" @default.
- W2355969766 hasPublicationYear "2005" @default.
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