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- W2355982904 abstract "Objective: To explore the effect of gamma irradiation on nuclear factor-kappa B in cultured bone marrow stromal cells. Methods: Immunocytochemistry, Western blot and electrophoretic mobility shift assay (EMSA) were used. Results: The expression of NF-kB in cultured mouse bone marrow stromal cells (BM-SCs) on the level of protein was elevated after exposure to 60Co in the dosage of 8. 0 Gy with the use of im-munocytochemistry and Western blot. The activity of nuclear factor-kappa B in cultured BMSCs was significantly increased after exposure to gamma irradiation by using EMSA. The activity peak was at the 4th h after irradiation. Conclusion: Our results suggest that the activation of nuclear factor-kappa B in the BMSCs after irradiation may be involved in the protection of BMSCs against apoptosis and in the recovery of hematopoiesis after radiation." @default.
- W2355982904 created "2016-06-24" @default.
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- W2355982904 date "2002-01-01" @default.
- W2355982904 modified "2023-09-23" @default.
- W2355982904 title "Effect of gamma irradiation on nuclear factor-kappa B in cultured bone marrow stromal cells" @default.
- W2355982904 hasPublicationYear "2002" @default.
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