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- W2356013804 abstract "Objective To investigate the growth inhibition of antisense oligonucleotides of telomerase on liver tumor cell enhanced by nanoparticles. Methods Chitosan nanoparticles were prepared and antisense oligonucleotides of telomerase were carried in them. Influence of antisense oligonucleotides of telomeras on telomerase was studied by TRAP-ELASA method. The inhibition of antisense oligonucleotides of telomerase on HEPG2 growth was studied by MTT method. Results Antisense oligonucleotides of telomerase carried by chitosan nanoparticles could enhance inhibition of liver tumor cell and telomerase. Conclusion Albumin nanoparticle can be used as an effective carrier in antisense technology." @default.
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- W2356013804 date "2008-01-01" @default.
- W2356013804 modified "2023-09-22" @default.
- W2356013804 title "Therapy of liver tumor by antisense oligonucleotides of telomerase carried in nanoparticles" @default.
- W2356013804 hasPublicationYear "2008" @default.
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