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- W2356054363 abstract "Objective:To investigate the possible interaction of Lp(a), and Lp(a) circulating immune complexes (CIC) 〔Lp(a)-CIC〕 level with triglyceride (TG). Methods:Plasma Lp(a), Lp(a)-CIC and LDL-CIC levels were determined by ELISAs in 232 patients with various dyslipidaemias, respectively. Results:Hypertriglyceridaemic patients exhibited the lowest plasma Lp(a) levels, while hypercholesterolaemic patients exhibited the highest. Patients with mixed hyperlipidaemia had intermediate serum Lp(a) concentrations, which were significantly lower than those in the controls. Interestingly, we also found that hypertriglyceridaemic patients exhibited the lowest plasma Lp(a)-CIC and LDL-CIC levels, while hypercholesterolaemic patients exhibited the highest. TG levels were negatively correlated with Lp(a) (r=-0.15, P0.05), Lp(a)-CIC (r=-0.20, P0.01), and LDL-CIC (r=-0.214, P 0.01) concentrations, respectively. Furthermore, significantly positive relationships were found between Lp(a)-CIC and Lp(a) levels (r=0.65, P0.001), and between LDL-CIC and LDL-C levels (r= 0.43, P0.001), respectively. Conclusion:The plasma Lp(a) and its circulating immune complexes levels decrease in hypertriglyceridaemic patients. According to different concentrations of Lp(a) and LDL, their circulating immune complexes levels might change." @default.
- W2356054363 created "2016-06-24" @default.
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- W2356054363 date "2004-01-01" @default.
- W2356054363 modified "2023-09-25" @default.
- W2356054363 title "Lipoprotein (a) and its immune complexes concentrations in patients with various dyslipidaemias" @default.
- W2356054363 hasPublicationYear "2004" @default.
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