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- W2356054927 abstract "Objective To explore the change rule of intestinal mucosal permeability in patients with peritonitis and the effect of rhGH on it. Methods Forty patients with acute diffuse peritonitis were divided randomly into two groups: common treatment group ( n =20) and GH treatment group ( n =20). Ten healthy adults were taken as the normal control group. All the patients were operated in 24 h after hospitalization. The patients in GH treatment group were given a subcutaneous injection of 8 unit rhGH daily for 7 d. Their other treatments were same as those of common treatment group. All the patients took nonmetabolizable 99 Tc m DTPA orally on 1,4,8 d after operation and 99 Tc m DTPA in urine was determined to assess their intestinal mucosal permeability. Besides, their clinical condition, nutritional status and treatment results were also observed. Results Intestinal mucosal permeability of patients in the common treatment group increased significantly. Intestinal mucosal permeability descented faster in the rhGH treatment group than that in the common treatment group. Compared with the common treatment group, the patients in the rhGH treatment group had sooner recovery, fewer complications, better nutritional status, leukocyte count descented faster and the length of hospitalization was shorter. Conclusion Intestinal mucosal permeability increases significantly in patients with peritonitis. GH plays a protective role in intestinal mucosal permeability and helps to improve treatment results." @default.
- W2356054927 created "2016-06-24" @default.
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- W2356054927 date "2002-01-01" @default.
- W2356054927 modified "2023-09-23" @default.
- W2356054927 title "Effect of growth hormone on intestinal mucosal barrier of peritonitis patients" @default.
- W2356054927 hasPublicationYear "2002" @default.
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