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- W2356072169 abstract "The Nobel Prize in Physiology or Medicine in 2011 was awarded to Bruce A.Beutler and Jules A.Hoffmann for their discoveries of the pattern-recognition receptors(PRRs) in innate immunity,and Ralph M.Steinman for his discovery of the dendritic cells(DCs) and their roles in adaptive immunity.Host recognizes invading pathogens through PRRs in innate immunity,and pathogen-associated peptides processed by DCs are presented to the T cells to activate adaptive immunity.This review will summarize the history for the discoveries of PRRs and DCs,introduce the latest advances and discuss their applications in the treatment of related diseases." @default.
- W2356072169 created "2016-06-24" @default.
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- W2356072169 date "2011-01-01" @default.
- W2356072169 modified "2023-09-23" @default.
- W2356072169 title "Discovery and significance of pattern-recognition receptors and dendritic cells" @default.
- W2356072169 hasPublicationYear "2011" @default.
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