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- W2356093220 abstract "Objective:To observe effect of Yiqi Huoxue Decoction(YHD)on serum levels of endothelin-1(ET-1)and nitric oxide(NO)in patients with chronic pul- monary heart disease(CPHD)acute exacerbation.Methods:Eighty patients were equal- ly randomized into two groups.The two groups received routine treatment for anti-inflam- mation,relieving spasm and asthan,and oxygen inhalation,and the treatment group re- ceived oral use of YHD additionally.The treatment lasted 14 days.Results:The markedly effective rate was 62.5% and the total effective rate was 97.5% in the treat- ment group,and was 32.5% and 80.0% in the control group respectively,the differ- ence being significant(P0.05).Serum ET-1 level decreased and NO content in- creased in the two groups after treatment(P0.05 compared with those before treat- ment),and the changes of the ET-1 and NO were obvious in the treatment group(P0.01 compared with the control group).The effect on improving hemorheological index- es,increasing partial pressure of oxygen in artery,and decreasing partial pressure of car- bon dioxide in the treatment group was superior to the controI group(P0.05).Con- clusion:YHD has certain effect for chronic pulmonary heart disease acute exacerbation and the therapeutic mechanism may be related with the decrease of pulmonary artery pres- sure by decreasing serum ET-1 and increasing NO." @default.
- W2356093220 created "2016-06-24" @default.
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- W2356093220 date "2008-01-01" @default.
- W2356093220 modified "2023-09-24" @default.
- W2356093220 title "Effect of Yiqi Huoxue Decoction on Serum Levels of EndotheUn-1 and Nitric Oxide in Patients with Chronic Pulmonary Heart Disease Acute Exacerbation" @default.
- W2356093220 hasPublicationYear "2008" @default.
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