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- W2356107782 abstract "Objective Discussing clinical effect and adverse effects of FolFox4 proposal and Xelox proposal for advanced colorectal cancer treatment on frontline.Methods In the study,64 patients with advanced colorectal cancer are randomly assigned to two teams.FolFox4 team adopts L-OHP 85 mg/m2,CF 200 mg/m2,5-FU 1 000 mg/m2,repeat the same action every 2 weeks and 28 days as a cycle.Xelox team adopts L-OHP 130 mg/m2,Xeloda 1 800 mg/(m2·d) d1-14,and 21 days as a cycle.It takes 164 cycles for two teams together for chemotherapy.Clinical response and toxic adverse effects shall be recorded.Results The total effect of FolFox4 team is 56.3%(18/32),the median remission time is 7.5 month,the mediate survival time is 11month;meanwhile,The total effect of Xelox team is 46.9%(15/32),the median remission time is 7.0 month,the mediate survival time is 9.5 month.Therefore,by comparing two teams' results,it is concluded that there are not any significant differences for two teams on median remission time and mediate survival time.Conclusions In FolFox4 proposal and Xelox proposal for advanced colorectal cancer treatment on frontline,there are not any significant differences for the objective effect of colorectal cancer on median remission time and mediate survival time,and toxic adverse effects for two team is not hard;therefore,the two proposal shall be taken as the first option as doing the advanced colorectal cancer treatment on frontline." @default.
- W2356107782 created "2016-06-24" @default.
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- W2356107782 date "2011-01-01" @default.
- W2356107782 modified "2023-10-01" @default.
- W2356107782 title "Analysis of the FolFox4 Proposal and Xelox Proposal for Advanced Colorectal Cancer Treatment on Frontline" @default.
- W2356107782 hasPublicationYear "2011" @default.
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