FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2356168435> ?p ?o ?g. }

• W2356168435 endingPage "9" @default.
• W2356168435 startingPage "431" @default.
• W2356168435 abstract "To observe the effect of electroacupuncture (EA) and moxibustion-like thermal stimulation with different temperatures at Zusanli (ST 36) on pain reactions in transient receptor potential vanilloid type 1 knock-out (TRPV 1 -/-) mice so as to study its mechanisms underlying analgesia.Ten C 57 BL/6 mice and 10 TRPV 1 -/- mice were respectively divided into control and TRPV 1 -/- groups. EA (0.3 mA, 1.0 mA, 3.0 mA) or thermal water-bath (38 degrees C, 43 degrees C, 46 degrees C) stimulation was applied to the right ST 36 for 20 min and 10 min, respectively. Mechanical and thermal pain thresholds of the bilateral paws were detected before and immediately after stimulation, and 5 min after EA stimulation at 0.3 mA, 3.0 mA and thermal water-bath stimulation at 38 degrees C, 46 degrees C, separately.(1) The thermal threshold was significantly higher in TRPV 1 -/- mice than in C 57 BL/6 mice (P < 0.001). (2) In C 57 BL/6 mice, both homolateral and contralateral mechanical and thermal pain thresholds were significantly increased following 1.0 mA, 3.0 mA EA, and 43 degrees C and 46 degrees C thermal stimulation of the right Zusanli (ST 36) (P < 0.05, P < 0.01, P < 0.001); while only homolateral mechanical and thermal pain thresholds were increased after 0.3 mA EA and 38 degrees C thermal stimulation of ST36 (P < 0.05, P < 0.01). In TRPV 1 -/- mice group, both homolateral and contralateral mechanical and thermal pain thresholds were significantly increased by 3.0 mA EA stimulation of ST 36 (P < 0.05, P < 0.01). Bilateral mechanical thresholds and homolateral thermal threshold were significantly increased by 1.0 mA EA stimulation of ST 36 (P < 0.05, P < 0.01), while only homolateral mechanical and thermal pain thresholds were increased by 0.3 mA EA, and 43 degrees C and 46 degrees C thermal stimulation (P < 0.05, P < 0.01). Additionally, only the homolateral mechanical threshold was increased by 38 degrees C thermal stimulation (P < 0.05). (3) The mechanical and thermal pain thresholds of the bilateral limbs were increased to some extent in TRPV 1 -/- mice compared with those of C 57 BL/6 mice following EA and thermal stimulation of the right ST 36. (4) Five minutes after 0.3 mA, 3.0 mA EA and 38 degrees C, 46 degrees C thermal water-bath stimulation, both mechanical and thermal pain thresholds recovered to their baseline levels in both TRPV 1 -/- and C 57 BL/6 mice.Both EA and thermal stimulation of the right ST 36 can raise mechanical and thermal pain thresholds in TRPV 1 -/- and C 57 BL/6 mice, but needing a stronger stimulation in TRPV 1 -/- mice, suggesting an involvement of TRPV 1 receptors in analgesia." @default.
• W2356168435 created "2016-06-24" @default.
• W2356168435 creator A5006218908 @default.
• W2356168435 creator A5018058464 @default.
• W2356168435 creator A5021529881 @default.
• W2356168435 creator A5053847454 @default.
• W2356168435 creator A5055555579 @default.
• W2356168435 creator A5062840485 @default.
• W2356168435 creator A5080278566 @default.
• W2356168435 creator A5081220083 @default.
• W2356168435 creator A5089053594 @default.
• W2356168435 date "2012-12-01" @default.
• W2356168435 modified "2023-09-27" @default.
• W2356168435 title "[Effects of electroacupuncture and regional thermal stimulation at Zusanli (ST 36) on pain thresholds of TRPV 1 knock-out mice]." @default.
• W2356168435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23383450" @default.
• W2356168435 hasPublicationYear "2012" @default.
• W2356168435 type Work @default.
• W2356168435 sameAs 2356168435 @default.
• W2356168435 citedByCount "5" @default.
• W2356168435 countsByYear W23561684352015 @default.
• W2356168435 countsByYear W23561684352017 @default.
• W2356168435 countsByYear W23561684352018 @default.
• W2356168435 countsByYear W23561684352020 @default.
• W2356168435 countsByYear W23561684352022 @default.
• W2356168435 crossrefType "journal-article" @default.
• W2356168435 hasAuthorship W2356168435A5006218908 @default.
• W2356168435 hasAuthorship W2356168435A5018058464 @default.
• W2356168435 hasAuthorship W2356168435A5021529881 @default.
• W2356168435 hasAuthorship W2356168435A5053847454 @default.
• W2356168435 hasAuthorship W2356168435A5055555579 @default.
• W2356168435 hasAuthorship W2356168435A5062840485 @default.
• W2356168435 hasAuthorship W2356168435A5080278566 @default.
• W2356168435 hasAuthorship W2356168435A5081220083 @default.
• W2356168435 hasAuthorship W2356168435A5089053594 @default.
• W2356168435 hasConcept C126322002 @default.
• W2356168435 hasConcept C134018914 @default.
• W2356168435 hasConcept C142724271 @default.
• W2356168435 hasConcept C155164980 @default.
• W2356168435 hasConcept C160145004 @default.
• W2356168435 hasConcept C170493617 @default.
• W2356168435 hasConcept C204787440 @default.
• W2356168435 hasConcept C24998067 @default.
• W2356168435 hasConcept C2776202274 @default.
• W2356168435 hasConcept C2777674692 @default.
• W2356168435 hasConcept C2779504368 @default.
• W2356168435 hasConcept C42219234 @default.
• W2356168435 hasConcept C56837625 @default.
• W2356168435 hasConcept C71924100 @default.
• W2356168435 hasConcept C87649029 @default.
• W2356168435 hasConceptScore W2356168435C126322002 @default.
• W2356168435 hasConceptScore W2356168435C134018914 @default.
• W2356168435 hasConceptScore W2356168435C142724271 @default.
• W2356168435 hasConceptScore W2356168435C155164980 @default.
• W2356168435 hasConceptScore W2356168435C160145004 @default.
• W2356168435 hasConceptScore W2356168435C170493617 @default.
• W2356168435 hasConceptScore W2356168435C204787440 @default.
• W2356168435 hasConceptScore W2356168435C24998067 @default.
• W2356168435 hasConceptScore W2356168435C2776202274 @default.
• W2356168435 hasConceptScore W2356168435C2777674692 @default.
• W2356168435 hasConceptScore W2356168435C2779504368 @default.
• W2356168435 hasConceptScore W2356168435C42219234 @default.
• W2356168435 hasConceptScore W2356168435C56837625 @default.
• W2356168435 hasConceptScore W2356168435C71924100 @default.
• W2356168435 hasConceptScore W2356168435C87649029 @default.
• W2356168435 hasIssue "6" @default.
• W2356168435 hasLocation W23561684351 @default.
• W2356168435 hasOpenAccess W2356168435 @default.
• W2356168435 hasPrimaryLocation W23561684351 @default.
• W2356168435 hasRelatedWork W2064416809 @default.
• W2356168435 hasRelatedWork W2130243588 @default.
• W2356168435 hasRelatedWork W2356168435 @default.
• W2356168435 hasRelatedWork W2361283397 @default.
• W2356168435 hasRelatedWork W2361890319 @default.
• W2356168435 hasRelatedWork W2376539174 @default.
• W2356168435 hasRelatedWork W2382002724 @default.
• W2356168435 hasRelatedWork W2996236703 @default.
• W2356168435 hasRelatedWork W4200106852 @default.
• W2356168435 hasRelatedWork W955873031 @default.
• W2356168435 hasVolume "37" @default.
• W2356168435 isParatext "false" @default.
• W2356168435 isRetracted "false" @default.
• W2356168435 magId "2356168435" @default.
• W2356168435 workType "article" @default.